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排序方式: 共有388条查询结果,搜索用时 15 毫秒
381.
382.
Strong and weak tests of macroecological theory 总被引:10,自引:1,他引:9
383.
Coconversion of flanking sequences with homothallic switching 总被引:16,自引:0,他引:16
Homothallic switching in S. cerevisiae involves replacing the DNA of the expressed allele at the mating type locus (MAT) with a duplicate of sequences from the unexpressed loci HML or HMR. The MATa and MAT alpha alleles differ by a DNA substitution that is flanked by sequences in common to MAT, and the donor loci HML and HMR. Using restriction site polymorphisms between MAT and the donor loci, we demonstrate that the extent of MAT DNA that is replaced during switching is variable and that there is a gradient of coconversion across the X region. Coconversion events occur on both sides of the double-strand cleavage by the HO gene product. The two cells produced after a switch often differ at the flanking site, indicating a DNA heteroduplex intermediate. 相似文献
384.
Andreas Zankl Emma?L. Duncan Paul?J. Leo Graeme?R. Clark Evgeny?A. Glazov Marie-Claude Addor Troels Herlin Chong?Ae Kim Bruno?P. Leheup Jim McGill Steven McTaggart Stephen Mittas Anna?L. Mitchell Geert?R. Mortier Stephen?P. Robertson Marie Schroeder Paulien Terhal Matthew?A. Brown 《American journal of human genetics》2014,94(4):643
385.
386.
M McGill 《Cytogenetics and cell genetics》1980,26(2-4):117-126
Small lymphocytes differentiate into functionally active blast cells in vitro upon stimulation with such mitogens as phytohemagglutinin and sodium periodate. If stimulated lymphocytes are subsequently treated with the nucleic acid intercalating dye ethidium bromide, electron-dense complexes containing nucleic acid are formed in mitochondria, protein synthesis in mitochondria is inhibited, and lymphoblast division ceases. Formation of complexes and the development of morphologically abnormal mitochondria provide ultrastructural evidence of mitochondrial protein inhibition and serve as markers for mitogen-responsive lymphocytes. The formation of these abnormalities in all mitochondria of treated megakaryocytes and 22% of mitochondria in platelets indicates that platelets contain functional nucleic acid and that the induced structural changes may be occurring in a less-differentiated (i.e., younger) subpopulation of circulating platelets. 相似文献
387.
Elizabeth M. Alder John Godfrey Thomas E. McGill Kenneth R. Watt 《Animal behaviour》1981,29(3):942-952
The sexual behaviour of bank voles from the mainland of Great Britain, and from the island of Skomer, differs in a number of respects. Voles from the mainland population show in general greater sexual activity. These variations may be understood as adaptations to ecological differences, particularly in population density. The reciprocal hybrids resemble the mainland population in a number of aspects of their mating behaviour. The possible evolutionary importance of this dominance is discussed. The behaviour of the bank vole is put into the perspective of generalizations made about other mammals. The separate influence of the male and of the female on quantitative variation between the two forms was investigated by studying mating between members of different populations. Some aspects of mating behaviour are shown to be due primarily to the male, others primarily to the female and others to the particular combinations involved. This situation is discussed in relation to the separate action of natural selection on members of each sex. 相似文献
388.
Michael L. Thompson Thomas E. McGill Stephen M. McIntosh Aubrey Manning 《Animal behaviour》1976,24(3):519-522
Two experiments investigate the effects of adrenalectomy on the capacity of male mice of the BDF1 genotype (C57B1/6Fa♀×DBA/2♂) to retain sexual behaviour following castration. Adrenalectomy is without effect and it is suggested that androgens can play no part in the maintenance of sexual behaviour in these castrates. 相似文献